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Article

Comparison of KRAS mutation analysis of colorectal cancer samples by standard testing and next-generation sequencing.

Journal of clinical pathology - 1 Sept 2014

Kothari Nishi, Schell Michael J, Teer Jamie K, Yeatman Timothy, Shibata David, Kim Richard

Abstract excerpt

AIMS: Based on KRAS testing, the subset of patients with metastatic colorectal cancer (CRC) that could benefit from anti-EGFR therapy can be better delineated. Though KRAS testing has become significantly more prevalent over the last few years, methods for testing remain heterogeneous and discordance has been reported between methods. METHODS: In this study, we examined a CRC patient population and compared KRAS...

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Source

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Identifiers

PMID: 25004944
DOI: 10.1136/jclinpath-2014-202405
PMCID: PMC4743643

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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