Article
BRAF mutation testing in solid tumors: a methodological comparison.
The Journal of molecular diagnostics : JMD - 1 Sept 2014
Weyant Grace W, Wisotzkey Jeffrey D, Benko Floyd A, Donaldson Keri J
Abstract excerpt
Solid tumor genotyping has become standard of care for the characterization of proto-oncogene mutational status, which has traditionally been accomplished with Sanger sequencing. However, companion diagnostic assays and comparable laboratory-developed tests are becoming increasingly popular, such as the cobas 4800 BRAF V600 Mutation Test and the INFINITI KRAS-BRAF assay, respectively. This study evaluates and...
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