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Article

The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer.

Histopathology - 1 Sept 2014

Boyle David P, McArt Darragh G, Irwin Gareth, Wilhelm-Benartzi Charlotte S, Lioe Tong F, Sebastian Elena, McQuaid Stephen, Hamilton Peter W, James Jacqueline A, Mullan Paul B, Catherwood Mark A, Harkin D Paul, Salto-Tellez Manuel

Abstract excerpt

AIMS: The utility of p53 as a prognostic assay has been elusive. The aims of this study were to describe a novel, reproducible scoring system and assess the relationship between differential p53 immunohistochemistry (IHC) expression patterns, TP53 mutation status and patient outcomes in breast cancer. METHODS AND RESULTS: Tissue microarrays were used to study p53 IHC expression patterns: expression was defined as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24612173
DOI: 10.1111/his.12398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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