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Article

Amplified single base-pair mismatch detection via aggregation of exonuclease-sheared gold nanoparticles.

Analytical chemistry - 1 Apr 2014

Wu Shuo, Liang Pingping, Yu Haixiang, Xu Xiaowen, Liu Yuan, Lou Xinhui, Xiao Yi

Abstract excerpt

Single nucleotide polymorphism (SNP) detection is important for early diagnosis, clinical prognostics, and disease prevention, and a rapid and sensitive low-cost SNP detection assay would be valuable for resource-limited clinical settings. We present a simple platform that enables sensitive, naked-eye detection of SNPs with minimal reagent and equipment requirements at room temperature within 15 min. SNP...

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Share to Base Pair Mismatch
Share to Exonucleases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 24611947
DOI: 10.1021/ac4040373
PMCID: PMC3982981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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