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Article

Femtomolar oligonucleotide detection by a one-step gold nanoparticle-based assay.

Colloids and surfaces. B, Biointerfaces - 1 Nov 2015

Rajendran Prayanka, Kaufmann Silvan, Vörös János, Zenobi-Wong Marcy, Demkó László

Abstract excerpt

A sequence-specific oligonucleotide detection method based on the tail-to-tail aggregation of functionalized gold nanoparticles in the presence of target analytes is presented together with its optimization and capabilities for detection of single nucleotide polymorphisms (SNPs). In this single-step method, capture probes are freely accessible for hybridization, resulting in an improved assay performance compared...

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PMID: 26263211
DOI: 10.1016/j.colsurfb.2015.07.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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