Article
An eQTL analysis of the human glioblastoma multiforme genome.
Genomics - 1 Apr 2014
Shpak Max, Hall Amelia Weber, Goldberg Marcus M, Derryberry Dakota Z, Ni Yunyun, Iyer Vishwanath R, Cowperthwaite Matthew C
Abstract excerpt
In this paper we use eQTL mapping to identify associations between gene dysregulation and single nucleotide polymorphism (SNP) genotypes in glioblastoma multiforme (GBM). A set of 532,954 SNPs was evaluated as predictors of the expression levels of 22,279 expression probes. We identified SNPs associated with fold change in expression level rather than raw expression levels in the tumor. Following adjustment for...
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