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Chromosomal instability portends superior response of rectal adenocarcinoma to chemoradiation therapy

6 Mar 2014

Abstract excerpt

BACKGROUND: Persistent chromosome segregation errors represent a conspicuous feature of human neoplasms. It is widely accepted that this chromosomal instability is associated with poor prognosis; however, its effect on therapeutic response is a matter of conjecture. METHODS: Here, the role of chromosome segregation errors in the response of patients with rectal adenocarcinoma to chemoradiation therapy (CRT) was...

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PMID: 24604319
DOI: 10.1002/cncr.28656

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