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Article

Radiotherapy Response in Microsatellite Instability Related Rectal Cancer

1 Jan 2013

Abstract excerpt

Preoperative radiotherapy may improve the resectability and subsequent local control of rectal cancers. However, the extent of radiation induced regression in these tumours varies widely between individuals. To date no reliable predictive marker of radiation sensitivity in rectal cancer has been identified. At the cellular level, radiation injury initiates a complex molecular network of DNA damage response (DDR)...

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PMID: 23482947
DOI: 10.4132/koreanjpathol.2013.47.1.1

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