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Article

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.

British journal of cancer - 18 Mar 2014

Deb S, Xu H, Tuynman J, George J, Yan Y, Li J, Ward R L, Mortensen N, Hawkins N J, McKay M J, Ramsay R G, Fox S B

Abstract excerpt

BACKGROUND: RAD21 is a component of the cohesion complex and is integral to chromosome segregation and error-free DNA repair. RAD21 is functionally important in tumour progression but its role in colorectal carcinoma (CRC) is unclear. We therefore assessed its clinicopathological and prognostic s...

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Identifiers

PMID: 24548858
DOI: 10.1038/bjc.2014.31
PMCID: PMC3960611

Genes

RAD21
KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24548858-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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