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Article

FAS system deregulation in T-cell lymphoblastic lymphoma.

Cell death & disease - 6 Mar 2014

Villa-Morales M, Cobos M A, González-Gugel E, Álvarez-Iglesias V, Martínez B, Piris M A, Carracedo A, Benítez J, Fernández-Piqueras J

Abstract excerpt

The acquisition of resistance towards FAS-mediated apoptosis may be required for tumor formation. Tumors from various histological origins exhibit FAS mutations, the most frequent being hematological malignancies. However, data regarding FAS mutations or FAS signaling alterations are still lacking in precursor T-cell lymphoblastic lymphomas (T-LBLs). The available data on acute lymphoblastic leukemia, of...

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Source

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Identifiers

PMID: 24603338
DOI: 10.1038/cddis.2014.83
PMCID: PMC3973220

Genes

FAS
FASLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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