Article
Fas-induced apoptosis in B cells.
Apoptosis : an international journal on programmed cell death - 1 Oct 2003
Mizuno T, Zhong X, Rothstein T L
Abstract excerpt
Engagement of the cell surface receptor Fas/APO-1 (CD95) initiates a sequence of intracellular events that leads to apoptotic cell death, and this outcome occurs in B cells as it does in other cell types. Fas signaling for B cell death is of particular interest because the expression and function of Fas is altered by engagement of additional cell surface receptors, leading to marked receptor-specific variation in...
Topics
- Animals
- Apoptosis
- Autoimmunity
- B-Lymphocytes
- Bone Marrow
- Fas Ligand Protein
- Humans
- Lymphoma
- Membrane Glycoproteins
- Mice
- Mutation
- Signal Transduction
- T-Lymphocytes
- fas Receptor