Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical, immunological, and pathological consequences of Fas-deficient conditions.

Lancet (London, England) - 14 Sept 1996

Le Deist F, Emile J F, Rieux-Laucat F, Benkerrou M, Roberts I, Brousse N, Fischer A

Abstract excerpt

BACKGROUND: The surface molecule named Fas/CD95, which is expressed on activated lymphocytes, can trigger cell death following interaction with its ligand (Fas L). This Fas-Fas-L interaction is thought to be a major regulatory mechanism for controlling the life span of peripheral lymphocytes, and therefore autoimmunity. METHODS: We assessed clinical, immunological and pathological features in three children who...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Apoptosis
Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant, Newborn

Share to Mutation

Share to Spleen

Share to Syndrome

Source

Identifiers

PMID: 8806292
DOI: 10.1016/S0140-6736(96)02293-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical, immunological, and pathological consequences of Fas-deficient conditions.PMID 8806292Read ↗

Missense Mutations in the Fas Gene Resulting in Autoimmune Lymphoproliferative Syndrome: A Molecular and Immunological AnalysisSemantic proximity Read ↗

Autoimmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype.Semantic proximity Read ↗

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.Semantic proximity Read ↗

The genetic landscape of the FAS pathway deficiencies.Semantic proximity Read ↗

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte ApoptosisSemantic proximity Read ↗

Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations.Semantic proximity Read ↗

FADD Deficiency Mimicking ALPS-FAS: An Expanding Phenotype.Semantic proximity Read ↗

Immunologic evaluation and genetic defects of apoptosis in patients with autoimmune lymphoproliferative syndrome (ALPS).Semantic proximity Read ↗

Novel Compound Heterozygous Variants in the FAS Gene Lead to Fetal Onset of Autoimmune Lymphoproliferative Syndrome (ALPS).Semantic proximity Read ↗

Autoimmune lymphoproliferative syndrome.Semantic proximity Read ↗

Advances in autoimmune lymphoproliferative syndromes.Semantic proximity Read ↗

ALPS, FAS, and beyond: from inborn errors of immunity to acquired immunodeficiencies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.