In-silico analysis of FASLG gene resistance in Cancer Immunotherapy

Abstract excerpt

<title>Abstract</title> <p> Background The FASLG gene in the TNF superfamily binds with the receptor superfamily to induce apoptosis. FAS ligand and receptor interactions lead to a dominant nature in the immune process and control cellular death (apoptosis). The dynamism of the apoptotic-induced FASLG gene controls tumour-infiltrating lymphocytes and suppresses tumour responses called tumour counter-attacks. In...

Topics

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• Autoantibodies
• Cytotoxicity, Immunologic
• Fas Ligand Protein
• Homeostasis
• Immune Tolerance
• Mice, Mutant Strains
• Models, Immunological
• Neovascularization, Pathologic

Identifiers and source

Literature Corpus work

7c96a951-50e7-5900-ad27-fd16d0a6aa41

DOI

10.21203/rs.3.rs-6582476/v1