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Article

MHC associations with clinical and autoantibody manifestations in European SLE

6 Mar 2014

Abstract excerpt

Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease affecting multiple organ systems and characterized by autoantibody formation to nuclear components. Although genetic variation within the major histocompatibility complex (MHC) is associated with SLE, its role in the development of clinical manifestations and autoantibody production is not well defined. We conducted a meta-analysis of four...

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PMID: 24598797
DOI: 10.1038/gene.2014.6

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