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Article

Two Major Autoantibody Clusters in Systemic Lupus Erythematosus

21 Feb 2012

Abstract excerpt

Systemic lupus erythematosus is a chronic autoimmune disease of complex clinical presentation and etiology and is likely influenced by numerous genetic and environmental factors. While a large number of susceptibility genes have been identified, the production of antibodies against a distinct subset of nuclear proteins remains a primary distinguishing characteristic in disease diagnosis. However, the utility of...

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PMID: 22363785
DOI: 10.1371/journal.pone.0032001

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