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Article

Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.

European journal of human genetics : EJHG - 1 Aug 2007

Graham Robert R, Ortmann Ward, Rodine Peter, Espe Karl, Langefeld Carl, Lange Ethan, Williams Adrienne, Beck Stephanie, Kyogoku Chieko, Moser Kathy, Gaffney Patrick, Gregersen Peter K, Criswell Lindsey A, Harley John B, Behrens Timothy W

Abstract excerpt

The human leukocyte antigen (HLA) Class II antigen presentation alleles DR and DQ are associated with susceptibility to systemic lupus erythematosus (SLE) and the production of lupus-related autoantibodies. Here, we explore the effect of different combinations of Class II risk haplotypes in a lar...

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Identifiers

PMID: 17406641
DOI: 10.1038/sj.ejhg.5201827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17406641-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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