[Protective function of sigma-1 receptor in spinal cord motor neurons].

Abstract excerpt

Sigma-1 receptor plays a protective function in various tissues. It was shown recently that a mutation in the sigma-1 receptor results in appearance of Amyotrophic Lateral Sclerosis (ALS). In the central nervous system (CNS) the highest amounts of sigma-1 receptor are found in motoneurons of the spinal cord, where receptor is localized in subsurface cisternae of cholinergic postsynaptic densities. The sigma-1...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amyotrophic Lateral Sclerosis
• Share to Central Nervous System
• Share to Motor Neurons