Article
HLA-G polymorphism (rs16375) and acute rejection in liver transplant recipients.
Disease markers - 1 Jan 2014
Azarpira Negar, Aghdaie Mahdokht H, Kazemi Kurosh, Geramizadeh Bita, Darai Masumeh
Abstract excerpt
BACKGROUND: HLA-G molecules exhibit immunomodulatory properties that can delay graft rejection. The 14 bp insertion/deletion polymorphism (INDEL) (rs16375) influences the stability of final HLA-G mRNA and its soluble isoforms. OBJECTIVE: The present study aimed to investigate the possible association between this polymorphism and the incidence of acute rejection in Iranian liver transplant recipients. METHODS:...
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