Article
Frequency of HLA-G exon 8 polymorphisms and kidney allograft outcome in Iranian population.
Molecular biology reports - 1 Jun 2011
Aghdaie Mahdokht H, Azarpira Negar, Kazemi Kurosh, Geramizadeh Bita, Darai Masumeh, Malekhoseini Seid Ali
Abstract excerpt
The 14-bp polymorphism in exon 8 of the HLA-G gene is associated with HLA-G mRNA stability and the patterns of alternative isoform splicing and may influence the functionality of the HLA-G molecule. HLA-G expression was related to allograft acceptance and fewer episodes of acute rejection during heart, kidney and liver-kidney transplantation. In order to determine a possible correlation between the 14-bp...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
