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Article

Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity.

PloS one - 1 Jan 2014

Vu Linh Hai, Araki Tsuyoshi, Na Jianbo, Clemen Christoph S, Williams Jeffrey G, Eichinger Ludwig

Abstract excerpt

Cellular adaptation to changes in environmental osmolarity is crucial for cell survival. In Dictyostelium, STATc is a key regulator of the transcriptional response to hyperosmotic stress. Its phosphorylation and consequent activation is controlled by two signaling branches, one cGMP- and the other Ca(2+)-dependent, of which many signaling components have yet to be identified. The STATc stress signalling pathway...

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Identifiers

PMID: 24587195
DOI: 10.1371/journal.pone.0090025
PMCID: PMC3934975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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