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Article

MCPerm: a Monte Carlo permutation method for accurately correcting the multiple testing in a meta-analysis of genetic association studies.

PloS one - 1 Jan 2014

Jiang Yongshuai, Zhang Lanying, Kong Fanwu, Zhang Mingming, Lv Hongchao, Liu Guiyou, Liao Mingzhi, Feng Rennan, Li Jin, Zhang Ruijie

Abstract excerpt

Traditional permutation (TradPerm) tests are usually considered the gold standard for multiple testing corrections. However, they can be difficult to complete for the meta-analyses of genetic association studies based on multiple single nucleotide polymorphism loci as they depend on individual-level genotype and phenotype data to perform random shuffles, which are not easy to obtain. Most meta-analyses have...

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PMID: 24586601
DOI: 10.1371/journal.pone.0089212
PMCID: PMC3931718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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