Article
PERMORY: an LD-exploiting permutation test algorithm for powerful genome-wide association testing.
Bioinformatics (Oxford, England) - 1 Sept 2010
Pahl Roman, Schäfer Helmut
Abstract excerpt
MOTIVATION: In genome-wide association studies (GWAS) examining hundreds of thousands of genetic markers, the potentially high number of false positive findings requires statistical correction for multiple testing. Permutation tests are considered the gold standard for multiple testing correction in GWAS, because they simultaneously provide unbiased type I error control and high power. At the same time, they...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.