Association between MTHFR polymorphisms and acute myeloid leukemia risk: a meta-analysis.

doi:10.1371/journal.pone.0088823

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Association between MTHFR polymorphisms and acute myeloid leukemia risk: a meta-analysis.

PloS one - 1 Jan 2014

Qin Yu-Tao, Zhang Yong, Wu Fang, Su Yan, Lu Ge-Ning, Wang Ren-Sheng

Abstract excerpt

Previous observational studies investigating the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and acute myeloid leukemia risk (AML) have yielded inconsistent results. The aim of this study is to derive a more precise estimation of the association between MTHFR (C677T and A1298C) polymorphisms and acute myeloid leukemia risk. PubMed and Embase databases were systematically searched...

Topics

Genetic Association Studies
Genetic Predisposition to Disease
Humans
Leukemia, Myeloid, Acute
Methylenetetrahydrofolate Reductase (NADPH2)
Odds Ratio
Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 24586405
DOI: 10.1371/journal.pone.0088823
PMCID: PMC3930602

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics