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Article

MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: a meta-analysis.

Leukemia research - 1 Dec 2010

Wang Jing, Zhan Ping, Chen Bing, Zhou Rongfu, Yang Yonggong, Ouyang Jian

Abstract excerpt

To date, case-control studies on the association between methylenetetrahydrofolate reductase (MTHFR) C677T and childhood acute lymphoblastic leukemia have provided either controversial or inconclusive results. To clarify the effect of MTHFR C677T on the risk of childhood acute lymphoblastic leukemia, a meta-analysis of all case-control observational studies was performed. Heterogeneity (I(2)=65%, P<0.0001) for...

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Source

Identifiers

PMID: 20409583
DOI: 10.1016/j.leukres.2010.03.034

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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