Article
MTHFR gene polymorphism and risk of myeloid leukemia: a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2014
Dong Song, Liu Yueling, Chen Jieping
Abstract excerpt
An increasing body of evidence has shown that the amino acid changes at position 1298 might eliminate methylenetetrahydrofolate reductase (MTHFR) enzyme activity, leading to insufficient folic acid and subsequent human chromosome breakage. Epidemiological studies have linked MTHFR single-nucleoti...
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