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Article

Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes.

The Journal of allergy and clinical immunology - 1 Apr 2014

Baines Katherine J, Simpson Jodie L, Wood Lisa G, Scott Rodney J, Fibbens Naomi L, Powell Heather, Cowan Douglas C, Taylor D Robin, Cowan Jan O, Gibson Peter G

Abstract excerpt

BACKGROUND: Airway inflammation is associated with asthma exacerbation risk, treatment response, and disease mechanisms. OBJECTIVE: This study aimed to identify and validate a sputum gene expression signature that discriminates asthma inflammatory phenotypes. METHODS: An asthma phenotype biomarker discovery study generated gene expression profiles from induced sputum of 47 asthmatic patients. A clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24582314
DOI: 10.1016/j.jaci.2013.12.1091

Genes

CLC
CPA3
ALPL
CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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