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Article

Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma.

Immunity, inflammation and disease - 1 Mar 2020

Sánchez-Ovando Stephany, Baines Katherine J, Barker Daniel, Wark Peter A, Simpson Jodie L

Abstract excerpt

BACKGROUND: Both the six gene signature (6GS: CPA3, DNASE1L3, CLC, IL1B, ALPL, and CXCR2) and T-helper 2 signature (TH2S: CLCA1, SERPINB2, and POSTN) are proposed as biomarkers in the identification of inflammatory phenotypes of asthma in induced sputum and epithelial brushings, respectively. The aim of this study was to explore patterns of gene expression of known signatures, 6GS and TH2S in endobronchial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31903716
DOI: 10.1002/iid3.282
PMCID: PMC7016845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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