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Article

A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD.

International journal of chronic obstructive pulmonary disease - 1 Jan 2020

Baines Katherine J, Negewo Netsanet A, Gibson Peter G, Fu Juan-Juan, Simpson Jodie L, Wark Peter A B, Fricker Michael, McDonald Vanessa M

Abstract excerpt

Background: The 6 gene expression signature (6GS) predicts inflammatory phenotype, exacerbation risk, and corticosteroid responsiveness in asthma. In COPD, patterns of airway inflammation are similar, suggesting the 6GS may be useful. This study determines the diagnostic and prognostic ability of 6GS in predicting inflammatory phenotypes and exacerbation risk in COPD. Methods: We performed 2 studies: a...

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Identifiers

PMID: 32669843
DOI: 10.2147/COPD.S245519
PMCID: PMC7337431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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