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Single-cell RNA Sequencing Analysis of Sputum Cell Transcriptomes Reveals Pathways and Communication Networks That Contribute to the Pathogenesis of Asthma

2025-04-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Asthma is driven by complex interactions amongst structural airway cells, cells of the immune system, and the environmental. While sputum cell characterization has been instrumental in studying asthma pathogenesis and refining treatment strategies, the nuances of cellular transcriptomes and intercellular communication in asthmatic sputum remain poorly understood. <h4>Methods...

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Literature Corpus work
cc622bff-1908-500a-9046-2c276b8e9e3d
DOI
10.1101/2025.03.31.646405
Open publication

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Single-cell RNA Sequencing Analysis of Sputum Cell Transcriptomes Reveals Pathways and Communication Networks That Contribute to the Pathogenesis of AsthmaDOI 10.1101/2025.03.31.646405
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