Article
Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes.
The Journal of allergy and clinical immunology - 1 May 2010
Hastie Annette T, Moore Wendy C, Meyers Deborah A, Vestal Penny L, Li Huashi, Peters Stephen P, Bleecker Eugene R
Abstract excerpt
BACKGROUND: Patients with severe asthma have increased granulocytes in their sputum compared with patients with mild to moderate asthma. OBJECTIVE: We hypothesized that inflammatory granulocytes in sputum may identify specific asthma severity phenotypes and are associated with different patterns of inflammatory proteins in sputum supernatants. METHODS: This hypothesis was tested in 242 patients with asthma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.