Article
PARK2 and proinflammatory/anti-inflammatory cytokine gene interactions contribute to the susceptibility to leprosy: a case-control study of North Indian population.
BMJ open - 27 Feb 2014
Chopra Rupali, Kalaiarasan Ponnusamy, Ali Shafat, Srivastava Amit K, Aggarwal Shweta, Garg Vijay K, Bhattacharya Sambit N, Bamezai Rameshwar N K
Abstract excerpt
OBJECTIVES: Cytokines and related molecules in immune-response pathways seem important in deciding the outcome of the host-pathogen interactions towards different polar forms in leprosy. We studied the role of significant and functionally important single-nucleotide polymorphisms (SNPs) in these genes, published independently from our research group, through combined interaction with an additional analysis of the...
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