Article
Association of variants in BAT1-LTA-TNF-BTNL2 genes within 6p21.3 region show graded risk to leprosy in unrelated cohorts of Indian population.
Human genetics - 1 May 2012
Ali Shafat, Chopra Rupali, Aggarwal Shweta, Srivastava Amit Kumar, Kalaiarasan Ponnusamy, Malhotra Dheeraj, Gochhait Sailesh, Garg Vijay K, Bhattacharya S N, Bamezai Rameshwar N K
Abstract excerpt
Host immune response against Mycobacterium leprae plays an important role in providing resistance to infection and disease progression. Genome-wide linkage and association studies suggest the possibility of multiple risk loci within HLA (6p21.3) region. Any systematic study of relevance within the histocompatibility complex of importance in host immune response would be pertinent because of non-replication of the...
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