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Article

Plasma concentrations of the amyloid-β peptides in young volunteers: the influence of the APOE genotype.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Zimmermann Ruediger, Huber Ellen, Schamber Christine, Lelental Natalia, Mroczko Barbara, Brandner Sebastian, Maler Juan Manuel, Oberstein Timo, Szmitkowski Maciej, Rauh Manfred, Kornhuber Johannes, Lewczuk Piotr

Abstract excerpt

Changes in the concentrations of amyloid-β (Aβ) in the body fluids are the earliest alterations observed in Alzheimer's disease (AD), however, there is a lack of data about how early these alterations occur, before the onset of the clinical symptoms. APOE genotype is the most recognized genetic risk/protective factor of AD, meaning that a group of non-demented persons carrying ε4 allele is enriched in the...

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Identifiers

PMID: 24577473
DOI: 10.3233/JAD-132687

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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