Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.

Neurobiology of aging - 1 May 2009

Glodzik-Sobanska Lidia, Pirraglia Elizabeth, Brys Miroslaw, de Santi Susan, Mosconi Lisa, Rich Kenneth E, Switalski Remigiusz, Saint Louis Leslie, Sadowski Martin J, Martiniuk Frank, Mehta Pankaj, Pratico Domenico, Zinkowski Raymond P, Blennow Kaj, de Leon Mony J

Abstract excerpt

While cerebrospinal fluid (CSF) biomarkers are of use in the prediction and diagnosis of Alzheimer's disease our understanding of the background effects of age and the ApoE genotype is limited. Seventy-eight community-based normal volunteers (mean age 60+/-10 years, range 36-86) were examined to determine the relationships between CSF measures of total tau (T-tau), hyperphosphorylated tau (P-tau 231), amyloid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Dinoprost

Share to Oxidative Stress

Share to Peptide Fragments

Share to tau Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17920160
DOI: 10.1016/j.neurobiolaging.2007.08.019
PMCID: PMC2774788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.PMID 17920160Read ↗

CSF biomarkers in Alzheimer's disease and controls: associations with APOE genotype are modified by age.Semantic proximity Read ↗

Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype.Semantic proximity Read ↗

The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease.Semantic proximity Read ↗

Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele.Semantic proximity Read ↗

APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging.Semantic proximity Read ↗

Stability of CSF beta-amyloid(1-42) and tau levels by APOE genotype in Alzheimer patients.Semantic proximity Read ↗

Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.Semantic proximity Read ↗

Progression from MCI to AD: predictive value of CSF Aβ42 is modified by APOE genotype.Semantic proximity Read ↗

The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid.Semantic proximity Read ↗

CSF tau is related to apolipoprotein E genotype in early Alzheimer's disease.Semantic proximity Read ↗

CSF beta-amyloid, cognition, and APOE genotype in Alzheimer's disease.Semantic proximity Read ↗

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.