Article
Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study.
Neuroscience letters - 22 May 1998
Slooter A J, de Knijff P, Hofman A, Cruts M, Breteler M M, Van Broeckhoven C, Havekes L M, van Duijn C M
Abstract excerpt
The APOE*4 allele of the apolipoprotein E gene (APOE) is an important risk factor for Alzheimer's disease. It has been suggested that levels of apolipoprotein E (apoE) in plasma are increased in Alzheimer's disease. In this population-based study, we found that serum apoE levels were lower in Alzheimer patients compared to non-demented controls (0.75 micromol/l (SD 0.35), vs. 0.83 micromol/l (SD 0.40), P < 0.05)....
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