Article
Association of 2 neurotrophic factor polymorphisms with efficacy of paroxetine in patients with major depressive disorder in a Chinese population.
Therapeutic drug monitoring - 1 Oct 2014
Wang Xin-Chen, Xu Du-Juan, Chen Gui-Hai, Xia Quan, Liu Li-Na
Abstract excerpt
BACKGROUND: To evaluate the influence of the single nucleotide polymorphism (SNP) rs 6265 in the brain-derived neurotrophic factor (BDNF) gene and 21 SNPs of the glial cell line-derived neurotrophic factor (GDNF) gene on the efficacy of paroxetine in patients with major depressive disorder (MDD). METHODS: Genotyping for BDNF and GDNF polymorphisms was performed in 298 patients with MDD who started 20 mg...
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