Article
Family-based association study between brain-derived neurotrophic factor gene and major depressive disorder of Chinese descent.
Psychiatry research - 30 Sept 2009
Liu Xiaohua, Xu Yifeng, Jiang Sanduo, Cui Donghong, Qian Yiping, Jiang Kaida
Abstract excerpt
The genetic pathogenesis of major depressive disorder (MDD) has not been elucidated. It has been proposed that brain-derived neurotrophic factor (BDNF), as a member of the neurotrophin family, may be involved in the etiology and antidepressant response of MDD. The present study investigated the possible presence of an association between the BDNF gene and MDD. Single-marker transmission disequilibrium test (TDT),...
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