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Article

Functional divergence between the two P1-P2 stalk dimers on the ribosome in their interaction with ricin A chain.

The Biochemical journal - 15 May 2014

Grela Przemysław, Li Xiao-Ping, Tchórzewski Marek, Tumer Nilgun E

Abstract excerpt

The eukaryotic stalk, which is responsible for the recruitment of translation factors, is a pentamer containing two P1-P2 dimers with unclear modes of action. In Saccharomyces cerevisiae, P1/P2 proteins (individual P1 and P2 proteins) are organized into two distinct dimers, P1A-P2B and P1B-P2A. To investigate the functional contribution of each dimer on the ribosome, RTA (ricin A chain), which binds to the stalk...

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PMID: 24576056
DOI: 10.1042/BJ20140014
PMCID: PMC4100481

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SRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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