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Article

A dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated complex on ribosomes.

The Journal of cell biology - 5 Apr 2010

Koplin Ansgar, Preissler Steffen, Ilina Yulia, Koch Miriam, Scior Annika, Erhardt Marc, Deuerling Elke

Abstract excerpt

The yeast Hsp70/40 system SSB-RAC (stress 70 B-ribosome-associated complex) binds to ribosomes and contacts nascent polypeptides to assist cotranslational folding. In this study, we demonstrate that nascent polypeptide-associated complex (NAC), another ribosome-tethered system, is functionally connected to SSB-RAC and the cytosolic Hsp70 network. Simultaneous deletions of genes encoding NAC and SSB caused...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20368618
DOI: 10.1083/jcb.200910074
PMCID: PMC2854369

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated complex on ribosomes.PMID 20368618Read ↗

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