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Article

The amino terminal end determines the stability and assembling capacity of eukaryotic ribosomal stalk proteins P1 and P2.

Nucleic acids research - 1 May 2011

Camargo Hendricka, Nusspaumer Gretel, Abia David, Briceño Verónica, Remacha Miguel, Ballesta Juan P G

Abstract excerpt

The eukaryotic ribosomal proteins P1 and P2 bind to protein P0 through their N-terminal domain to form the essential ribosomal stalk. A mutational analysis points to amino acids at positions 2 and 3 as determinants for the drastic difference of Saccharomyces cerevisiae P1 and P2 half-life, and suggest different degradation mechanisms for each protein type. Moreover, the capacity to form P1/P2 heterodimers is...

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Identifiers

PMID: 21247875
DOI: 10.1093/nar/gkq1356
PMCID: PMC3089481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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