Article
Functional role of the C-terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2015
Imai Hirotatsu, Miyoshi Tomohiro, Murakami Ryo, Ito Kosuke, Ishino Yoshizumi, Uchiumi Toshio
Abstract excerpt
Two types of elongation factors alternate in their binding to the factor-binding center of the ribosome. Both binding events are accompanied by GTP hydrolysis and drive the translation elongation cycle. The multicopy ribosomal protein family, termed the stalk, contributes actively to the elongation process. Recent evidence indicates that the mobile C-terminal tail of archaeal stalk aP1 directly interacts with...
Topics
- Archaea
- Escherichia coli
- Genetic Vectors
- Mutation
- Peptide Elongation Factors
- Pyrococcus horikoshii
- RNA, Ribosomal, 23S
- Ribosomal Proteins
- Ribosome Subunits, Large, Archaeal
- Ricin