Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of serum C-reactive protein levels with lupus disease activity in the absence of measurable interferon-α and a C-reactive protein gene variant.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Jun 2014

Enocsson Helena, Sjöwall Christopher, Kastbom Alf, Skogh Thomas, Eloranta Maija-Leena, Rönnblom Lars, Wetterö Jonas

Abstract excerpt

OBJECTIVE: The type I interferon (IFN) system is important in the pathogenesis of systemic lupus erythematosus (SLE). We previously demonstrated an inhibitory effect of IFNα on interleukin-6 (IL-6)-induced C-reactive protein (CRP) in vitro, hypothetically explaining the poor correlation between disease activity and CRP levels in SLE. This study was undertaken to investigate disease activity, IL-6 levels, and CRP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to C-Reactive Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Interferon-alpha

Share to Interleukin-6

Share to Lupus Erythematosus, Systemic

Share to Severity of Illness Index

Share to Young Adult

Source

Identifiers

PMID: 24574329
DOI: 10.1002/art.38408

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of serum C-reactive protein levels with lupus disease activity in the absence of measurable interferon-α and a C-reactive protein gene variant.PMID 24574329Read ↗

C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205.Semantic proximity Read ↗

Association of Polymorphisms in C-Reactive Protein (CRP) Promoter -821 A>G, -390 C>A/T, and Plasma Interferon-α (IFN-α) with Plasma CRP Level in Javanese Systemic Lupus Erythematosus (SLE) Patients.Semantic proximity Read ↗

Associations of C-reactive protein isoforms with systemic lupus erythematosus phenotypes and disease activity.Semantic proximity Read ↗

C-reactive protein +1444CT (rs1130864) genetic polymorphism is associated with the susceptibility to systemic lupus erythematosus and C-reactive protein levels.Semantic proximity Read ↗

C-reactive protein gene polymorphisms in disease susceptibility and clinical manifestations of Korean systemic lupus erythematosus.Semantic proximity Read ↗

Genetic variation in C-reactive protein (CRP) gene may be associated with risk of systemic lupus erythematosus and CRP concentrations.Semantic proximity Read ↗

CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients.Semantic proximity Read ↗

C-reactive protein (CRP) polymorphisms and haplotypes are associated with SLE susceptibility and activity but not with serum CRP levels in Mexican population.Semantic proximity Read ↗

The presence of IFL3/4 rs12979860 C allele influences the in vitro IP-10 production by mononuclear cells from patients with systemic lupus erythematosus.Semantic proximity Read ↗

Genetic variation in the CRP promoter: association with systemic lupus erythematosus.Semantic proximity Read ↗

Association study of CRP gene in systemic sclerosis in European Caucasian population.Semantic proximity Read ↗

Unactivated leukocyte expression of C-reactive protein is minimal and not dependent on rs1205 genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.