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Article

Unactivated leukocyte expression of C-reactive protein is minimal and not dependent on rs1205 genotype.

Scientific reports - 11 Mar 2021

Best L G, Azure C, Martell K, Tsosie K S, Voels B

Abstract excerpt

C-reactive protein (CRP), a prominent component of the innate immune system, is implicated in the pathophysiology of many conditions. CRP production primarily occurs in the liver; but contributions from other tissues is unclear. The Genotype-Tissue Expression Portal shows essentially no expression in whole blood and reports in the literature are conflicting. Multiple genomic variants influence serum levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33707594
DOI: 10.1038/s41598-021-85272-9
PMCID: PMC7952394

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