Article

The endoplasmic reticulum promotes microtubule organization and region-specific disassembly to execute Compartmentalized Cell Elimination

2025-05-13

Abstract excerpt

<h4>Summary</h4> Specialized cells, such as neurons, die during development and disease. How subcellular organization and interactions across diverse compartments direct death is not well-understood. We examine this by studying the Compartmentalized Cell Elimination (CCE) developmental death program of the C. elegans tail-scaffolding cell (TSC). We find endoplasmic reticulum (ER) shape genes and the microtubule...

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Literature Corpus work: cbc91b23-a019-5ca3-af88-e5dc1af6a567
DOI: 10.1101/2025.05.08.652974

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