Article
RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS).
Atherosclerosis - 1 Apr 2014
Shendre Aditi, Irvin Marguerite R, Aouizerat Bradley E, Wiener Howard W, Vazquez Ana I, Anastos Kathryn, Lazar Jason, Liu Chenglong, Karim Roksana, Limdi Nita A, Cohen Mardge H, Golub Elizabeth T, Zhi Degui, Kaplan Robert C, Shrestha Sadeep
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the Ryanodine receptor 3 (RYR3) gene are associated with common carotid intima media thickness (CCA cIMT) in HIV-infected men. We evaluated SNPs in the RYR3 gene among HIV-infected women participating in Women's Interagency HIV Study (WIHS). METHODS: CCA cIMT was measured using B-mode ultrasound and the 838 SNPs in the RYR3 gene region were genotyped using the...
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