Article
Replication of RYR3 gene polymorphism association with cIMT among HIV-infected whites.
AIDS (London, England) - 31 Jul 2012
Shrestha Sadeep, Yan Qi, Joseph Gregory, Arnett Donna K, Martinson Jeremy J, Kingsley Lawrence A
Abstract excerpt
To replicate the association of variants in RYR3 gene with common carotid intima-media thickness (cIMT), a surrogate marker of atherosclerosis, we genotyped single nucleotide polymorphisms (SNPs) rs2229116 and rs7177922 in a sub-population of 244 HIV-positive and HIV-negative men. SNP rs2229116 was associated with common cIMT in HIV infected white men after adjusting for age and use of stavudine (d4T). The...
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