Article

HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression

2024-10-18

Abstract excerpt

<title>Abstract</title> <p>Chronic inflammation contributes to the prevalence of cardiovascular disease in people living with HIV (PLWH). The immune mechanisms driving atherosclerosis progression in PLWH remain unclear. This study conducted comprehensive assessments of medium-sized coronary arteries and aorta from deceased PLWH and controls without HIV using DNA/RNA assays, spatial transcriptomics, and high-resol...

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Literature Corpus work: dc19e99a-ab19-5240-a2d0-ff7a2e020bd0
DOI: 10.21203/rs.3.rs-5125826/v1

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