Article
Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy.
PLoS medicine - 1 Mar 2006
Foulkes Andrea S, Wohl David A, Frank Ian, Puleo Elaine, Restine Stephanie, Wolfe Megan L, Dube Michael P, Tebas Pablo, Reilly Muredach P
Abstract excerpt
BACKGROUND: Protease inhibitors (PIs) are associated with hypertriglyceridemia and atherogenic dyslipidemia. Identifying HIV-1-infected individuals who are at increased risk of PI-related dyslipidemia will facilitate therapeutic choices that maintain viral suppression while reducing risk of atherosclerotic diseases. Apolipoprotein C-III (apoC-III) gene variants, which vary by race/ethnicity, have been associated...
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