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Article

Runt-related transcription factor 3 is involved in the altered phenotype and function in ThPok-deficient invariant natural killer T cells.

Cellular & molecular immunology - 1 May 2014

Liu Xia, Yin Shengxia, Cao Wenqiang, Fan Wei, Yu Lei, Yin Li, Wang Lie, Wang Jianli

Abstract excerpt

The interplay between the CD4-lineage transcription factor ThPok and the CD8-lineage transcription factor, runt-related transcription factor 3 (Runx3), in T-cell development has been extensively documented. However, little is known about the roles of these transcription factors in invariant natural killer T (iNKT) cell development. CD1d-restricted iNKT cells are committed to the CD4(+)CD8(-) and CD4(-)CD8(-)...

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Identifiers

PMID: 24561456
DOI: 10.1038/cmi.2014.3
PMCID: PMC4085493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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