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Transforming growth factor-β promotes the postselection thymic development and peripheral function of interferon-γ-producing invariant natural killer T cells

2022-10-23

Abstract excerpt

Interferon-γ producing invariant natural killer T (iNKT1) cells are lipid reactive innate-like lymphocytes that are resident in the thymus and peripheral tissues where they protect against pathogenic infection. The thymic functions of iNKT1 cells are not fully elucidated but subsets of thymic iNKT cells modulate CD8 T cell, dendritic cell, B cell and thymic epithelial cell numbers or function. Here we show that a...

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Literature Corpus work
aebe0d76-2ba6-5809-bf81-bb3040c5c93c
DOI
10.1101/2022.10.23.513409
Open publication

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Transforming growth factor-β promotes the postselection thymic development and peripheral function of interferon-γ-producing invariant natural killer T cellsDOI 10.1101/2022.10.23.513409
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